ЭлБиб

ПИЩЕВАЯ ПРОМЫШЛЕННОСТЬ

7/2012

RAW MATERIALS AND ADDITIVES

тенсивное выведение, а также спо/

собность терять токсичность при

связывании с гидрофобными пище/

выми ингредиентами (жирами, фе/

нольными соединениями и белка/

ми) обеспечивает им пищевую безо/

пасность при оральном применении.

Научное доказательство их биологи/

ческой активности (гипохолестери/

немической, противоаллергической,

иммуностимулирующей, противо/

воспалительной, антираковой и др.)

делает их перспективными пищевы/

ми добавками для разработки функ/

циональных продукты питания, спо/

собствующих профилактике различ/

ных заболеваний.

Работа проводилась при финансо/

вой поддержке Министерства обра/

зования и науки Российской Феде/

рации за счет средств государствен/

ного контракта № 16.522.12.2018.

ЛИТЕРАТУРА

Guclu/Ustundag, O.

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properties,

applications

and

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The biological

action of saponins

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Rao, A.V.

Dietary saponins and

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Mitra, S.

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, Characterization, and

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P. 11432–11440.

Юдина, Т.П.

Мицеллярные

свойства сапонинов из корней

Saponaria officinalis L.,

культивиро/

ванной на территории Приморского

края/Т.П. Юдина//Хранение и пере/

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№ 4. – С. 33–35.

Солюбилизирующая

способ/

ность сапонинов корней

Saponaria

officinalis/

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between adjuvant

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2151.

U.S.

Food

and

Drug

Administration, Center for Food Safety

& Applied Nutrition. 2003. Code of

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Title 21–Food And Drugs Chapter I/

Food And Drug Administration,

Department Of Health And Human

Services Part 172/Food Additives

Permitted For Direct Addition To Food

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www.cfsan.fda.gov/lrd/FCF172.html

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U.S.

Food

and

Drug

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for Official Publications of

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12.

Japanese

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13.

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Safety evaluation of certain food

additives and contaminants.

Quilaia

extracts

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14.

Pat

. JP 60064919 (А), A61K31/

355; A61K9/14. Production of powdery

or granular vitamin E preparation/

Kojima Yukio, Takano Yasushi,

Shirakawa Youichi, Itou Makoto.

Assignee: Ajinomoto KK, Asahi Denka

Kogyo KK. Appl. № JP19830172527

19830919. – 1985/04/13.

15.

Pat

. FR 2945936 (A1), A61K8/

04; A61K9/10. Preparing aqueous

emulsion of oily active substance,

useful for e.g. cosmetic and food use,

comprises

mixing

hydrophilic

component (water and saponin

emulsifier),

mixing

lipophilic

components (substance and stabilizer)

and homogenizing/Epiphani Jean

Claude. Assignee: EPIPHANI JEAN

CLAUDE. Appl.№ FR20090002520

20090526. – 2010/12/03.

16.

Pat

. EP 2359698 (A1), WO

2011089249 (A1), A23D9/00; A23L1/

22. Compositions with a surfactant

system comprising saponins, and

lecithin/Schrader Dirk; Sabater/

Luentzel

Christppher;

Homner

Cornella. Assignee: SYMRISE AG [DE].

Appl. № EP20100151491 20100122. –

2011/08/24.

17.

Pat

. WO 2004111069 (A2) A23L1/

30; A61K8/97; A61Q19/00. New

saponin compound, saponin solution

containing the same a preparation

method thereof, and pharmaceutical

compositions, health foods and

cosmetics containing the saponin as an

active component/Choi Jang Youn.

Assignee: CHOI JANG YOUN [KR].

Appl.

№ WO2004KR01459

20040618. – 2004/12/23.

18.

Pat

. CN 101361568 (A) A23L1/29

Functional food capable of reinforcing

human immunity/Binchang Deng,

Zhenshan Zhang, Tao Wang. Assignee:

BINCHANG DENG [CN]. Appl.

№ CN20081058901

20080911. –

2009/02/11.

19.

Pat

. JP 2009234962 (A) A23L1/

30;

A61K31/704;

A61K36/28.

Depressant for absorbing neutral lipids

obtained from daisy, and saponin

compound and its application/

Muraoka

Osamu,

Yoshikawa

Masayuki, Morikawa Toshio, Matsuda

Hisashi. Assignee: UNIV KINKI, DIA

BETYM

[JP].

Appl.

№ JP20080081460

20080326. –

2009/10/15.

20.

Pat

. JP 2010030950 (A) A23L1/

30;

A61K31/704;

A61K36/00.

Prophylactic and therapeutic agent for

metabolic syndrome and functional

food/Nakai Tadanobu. Assignee:

NAKAI KOSAN KK [JP]. Appl.

№ JP20080194528 20080729. – 2010/

02/12.

21.

Adjvant

and haemolytic activities

of 47 saponins derived from medicinal

and food plants/K. Oda [et al.]//Biol.

Chem. – 2000. – V. 381. – P. 67–74.

22.

Oleszek, W.

Determination and

toxicity of Saponins from

Amaranthus

cruentus

Seeds/W. Oleszek, M.

Junkuszew, A. Stochmal//J. Agric.

Food Chem. – 1999. – № 47.

–

Р.

3685–3687.

23.

Определение

токсичности рас/

тительного эмульгатора – водного

экстракта из корней мыльнянки ле/

карственной

Saponaria officinalis

L./

Т.П. Юдина [и др.]//Изв. вузов. Пи/

щевая технология. – 2007. – № 5–

6. – C. 28–29.

24.

Studies

absorption,

distribution and metabolism of ginseng

in humans after oral administration/J.

Lee [et al.]//J Ethnopharm. – 2009. –

V.122. – No 1. – Р. 143–148.

25.

Pharmacokinetics

Tissue

Distribution,

Metabolism,

and

Excretion of Ginsenoside Rg1 in Rats/L.

Feng [et al.]//Arch. Pharm. Res. –

2010.

–

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26.

Solid

lipid nanoparticle (SLN)

formulations as a potential tool for the

reduction of cytotoxicity of saponins/

H. Van de Ven [et al.]//Pharmazie. –

2009. – V. 64. – N. 3. – P. 172–176.

27.

Пищевая

безопасность сапонинов

корней Saponaria officinalis/Т.П. Юдина

[и др.]//Изв. вузов. Пищевая техноло/

гия. – 2010. –№ 5–6. – С. 22–25.

28.

Shigeru, K.

Quillaja saponin can

modulate ovalbumin/induced IgE

allergic responses through regulation

of Th1/Th2 balance in a murine model/

K. Shigeru, M. Yoshinori//J. Agric.

Food Chem. – 2006. – V. 54. – P.

3271–3276.

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