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significant chemical variability, which is in correlation with the specific ecological

requirements of the species.

The evaluation of medicinal plant ecotypes for quantitative and qualitative

differences in secondary metabolites with regard to growth and development

of these species has been provided a possibility for successive introduction

with valuable genotypes as well as possibilities of sustainable technology of

reproduction.

The biological and chemical characterisation, multiplication of plant material,

selection and other pre-breeding studies have determined in many cases

nature populations with high productivity and a content of secondary metabolites.

The use of sustainable technologies, reproduction and assessment of their best

forms has allowed breeding of these medicinal species in controled conditions.

The Institute of Botany has created a collection of these rare medicinal

plants where selected seeds and reproductive materials are produced and

dispossible for breeding in agrosystems in the country too. With the assistance

of scientific programs, sponsored by Ministry of Education and Science and

UNDP, considerable progress has been achieved in cultivating these plant

species.

^

Acknowledgements:

The author is thank ful to the National Science Foundation,

Project B-907 of the Ministry of Education and Science, and UNDP for their financial

support, which made these studies possible.

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