ЭлБиб

Аграрная наука Евро-Северо-Востока, № 2 (57), 2017 г.

Systematic approach to the development of methods of prevention of gastro-intestinal

diseases in newborn calves

Burova O.A.,

Researcher,

Blokhin A.A.,

PhD. In Veterinary Medicine, Senior Researcher.

Scientific and Research Veterinary Institute of the Non-Chernozem Zone of the Russian

Federation, Nizhny Novgorod, Russia

The main condition for the prevention of diseases in calves in early postnatal period is the formation of an

optimal immunological status of cows-mothers, provision of colostral immunity and colonization resistance of mu-

cous membranes in newborn calves. Methods of prevention of gastro-intestinal diseases should be based on the key

provisions on the system “mother-fetus-newborn”. Our methods includes improving the immune status of different

age groups of cattle population united in the system “mother-fetus-newborn” and consists of two stages. In the first

stage pregnant cows three months before calving are given the remedy “Immoveton-Ks” at a dose 0f 52.5 mg/kg

BW. Then 2 months before calving cows are immunized with vaccine “Hiprobovis-4” at a dose of 3 ml with a

booster after 21-30 days. In the second stage newborn calves are given combination of some remedies: “Immoveton-

Ks” intramuscularly or subcutaneously at a dose of 52.5 mg /kg BW once daily on day 1, 2 and 7 of life; fermented

milk product “EM-Kurunga” orally at a dose of 150 ml from the second day of life 3 times a day for 10 days; Multi-

vitamin + Minerals intramuscularly at a single dose of 1.5 ml on day 8 of life. It is established that immunization

with the vaccine “Hiprobovis-4” against the background of correction of the immune status using “Immoveton-Ks”

provides for the production of the greatest quantity of specific antibodies. This indicates pronounced stimulating

effects of immunomodulator “Immoveton-Ks” on the formation of post-vaccination immunity. Preventive effective-

ness of the proposed method on farms with high prevalence of gastrointestinal diseases of calves was 90.5%, the

safety – 98.9%, average daily weight gain - 840g.

Key words:

calves, diseases of the digestive apparatus, prevention, system “mother-fetus-newbrn”

References

1. Gladkova N.A.

Bolezni telyat v rannem post-

natal'nom periode: Avtoref. diss… kandidata vet. nauk

[Diseases in calves in early postnatal period: Author’s

abstract of PhD thesis]. Sankt-Peterburg, 2000. 22 p.

2. Ozdemirov A.A., Anaev M.S., Aygubova S.A.,

Ramazanova D.M.

Zheludochno-kishechnye bolezni

molodnyaka krupnogo rogatogo skota v prikaspiyskom

regione Rossii

. [Gastrointestinal diseases in young cattle

in the Caspian region of Russia].

Veterinarnaya

patologiya

. 2013. no. 2. pp. 19-21.

3. Filimonov D.N.

Effektivnost' kompleksnogo

primeneniya antibiotika na osnove tsiprofloksatsina i

apramitsina s probiotikom metabolitnogo tipa pri zhe-

ludochno-kishechnykh zabolevaniyakh telyat

. [Effective-

ness of combined use of antibiotic based on ciprofloxacin

and apramycin with probiotic of metabolite type at gastro-

intestinal diseases in calves].

Voprosy normativno-pravo-

vogo regulirovaniya v veterinarii

. 2016. no. 2. pp. 61-65.

4. Isaev V.V., Kosorlukova

Z.Ya.

, Khrisanfova T.D.,

Korobova O.V. e. a.

Korrektsiya immunodefitsitov dlya

profilaktiki zheludochno-kishechnykh bolezney novorozh-

dennykh telyat

. [Correction of immunodeficiencies for

prevention of gastrointestinal diseases in calves].

Veterinarnaya patologiya

. 2005. no. 4. pp. 113-116.

5. Sisyagina E.P., Redzhepova G.R., Sisyagin P.N.

Novye sposoby korrektsii immunodefitsitov u telyat

. [New

methods for correction of immunodeficiencies in calves].

Veterinarnyy vrach

. 2009. no. 6. pp. 39-42.

6. Shakhov A.G., Retskiy M.I., Mas'yanov Yu.N.,

Zolotarev A.I. i dr.

Povyshenie effektivnosti spetsi-

ficheskoy profilaktiki faktornykh infektsiy putem korrektsii

antioksidantnogo i immunnogo statusa korov i telyat

[Enhancing effectiveness of specific prophylaxis of facto-

ry infections by correction of antioxidant and immune

status of cows and calves].

Veterinarnyy konsul'tant

2008. no. 23-24. pp. 7-11.

7. Volkova S.

Immunnyy status korov i ikh

potomstva

. [Immune status of cows and their offspring].

Veterinariya sel'skokhozyaystvennykh zhivotnykh

. 2011.

no. 11. pp. 26-27.

8. Khusainov R.F.

Kolostral'nyy immunitet i

vnutriutrobnoe infitsirovanie telyat virusom leykoza ot

korov-materey s razlichnoy stepen'yu vyrazhennosti

infektsionnogo protsessa: Avtoref. diss…. kandidata biol.

nauk

. [Colostral immunity and intrauterine infection of

calves with bovine leukemia virus from cows-mothers

with various severity of the leukemic process: Author’s

abstract of PhD thesis]. Ufa. 2009. 22 p.

9. Grigor'eva G.I., Arbuzova A.A., Kul'chits-

kaya M.A., Panitkov M.A.

Rol' mikroorganizmov (bak-

teriy i virusov) v vozniknovenii zheludochno-kishechnykh

zabolevaniy novorozhdennykh telyat

. [Role of microor-

ganisms (bacteria and viruses) in occurrence of gastroin-

testinal diseases in newborn calves].

Veterinarnaya

patologiya

. 2005. no. 4. pp. 108-113.

10. Gumerov V.G.

Diagnostika i spetsificheskaya

profilaktika respiratornykh i zheludochno-kishechnykh

infektsiy krupnogo rogatogo skota: Avtoref. diss….

doktora vet. nauk

. [Diagnosis and specific prophylaxis of

respiratory and gastrointestinal infections in cattle: Au-

thor’s abstract of DSc Thesis]. Kazan', 2016. 34 p.

11. Erina T.A.

Mikrobiotsenoz kishechnika i immu-

nnyy status novorozhdennykh telyat s raznym morfo-

funktsional'nym razvitiem i ikh korrektsiya: avtoref.

diss…. kandidata vet. nauk

. [Intestinal microbiozinosis

and immune status of newborn calves with various

morphofunctional development and its correction: Au-

thor’s abstract of PhD Thesis]. Voronezh, 2015. 23 p.

12. Plokhinskiy N.A.

Algoritmy biometrii. Pod red.

akad. AN USSR B. V. Gnedenko

. [Algorithms of biomet-

rics. Under the editorship of B.V.Gnedenko]. Moscow:

Izd-vo Mosk. gos. un-ta

, 1980. 150 p.

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