NED373392NED

Особо опасные болезни животных 77 6. Mucosal immunization and adjuvants: a brief overview of recent advances and challenges / J. Holmgren, C. Czerkinsky, K. Eriksson, A. Mharandi // Vaccine. – 2003. –Vol. 21. – P. 89–95. 7. Rabies DNA vaccine encoding lysosome targeted glycoprotein supplement- ed with EMULSIGEN D confers complete protection in pre-and post-exposure stud- ies in BALB/c mice / M. Kaur, A. Saxena, A. Rai, R. Bhatnagar // FASEB J. – 2010. – Vol. 24. – P. 173–183. 8. Review of Newcastle disease virus with particular references to immunity and vaccination / S.O. Al Garib, A.L. Gielkens, E. Druys, G. Koch // World's Poul- try Science Journal. – 2003. –Vol. 59. – P. 185–200. IMMUNOGENIC PROPERTIES OF THE MUCOSAL VACCINE AGAINST NEWCASTLE DISEASE CONTAINING EMULSIGEN  -D ADJUVANT M.A. Volkova 1 , I.A. Chvala 2 , D.L. Dolgov 3 1 leading research worker, PhD (Biology), FGBI «ARRIAH», Vladimir; Е-mail: volkovama@arriah.ru 2 senior research worker, PhD (Veterinary Medicine), FGBI «ARRIAH», Vladimir 3 senior research worker, PhD (Veterinary Medicine), FGBI «ARRIAH», Vladimir Summary The results of studying immunogenic properties of the intranasally- intraocularly inoculated mucosal vaccine against Newcastle disease contain- ing EMULSIGEN  -D are presented in the paper. The triple inoculation of the experimental mucosal vaccine resulted in a significant increase of HI and ELISA antibody titres in blood, lacrimal fluid and tracheal swabs of chicks as compared to the administration of the antigen alone. Key words: Newcastle disease, mucosal vaccines, adjuvant Электронная Научная СельскоХозяйственная Библиотека